Posted 4/5/2024, 9:45:47 AM
New Methods to Analyze and Optimize 5’ UTR Structures for Translation Regulation
- References research on regulating translation at 5' UTRs and predicting their secondary structure
- Discusses techniques for finding RNA binding sites and analyzing effects of mutations
- Explains tools for predicting internal ribosome entry sites (IRES) in cellular and viral RNAs
- Compares models that generate synthetic 5' UTRs to optimize translation efficiency
- Presents transformer models to predict 5' UTR structures and functions from sequence