Posted 12/18/2023, 4:54:04 PM
New AI Designs 'Super Proteins' With Record-High Target Binding Strengths and Biosensor Potential
- AI used to create proteins that bind strongly and specifically to difficult targets like hormones
- Highest ever interaction strength reported between computer-designed protein and target
- New deep learning methods used - RFdiffusion and ProteinMPNN
- Proteins retained binding abilities despite harsh conditions
- Integrated protein into biosensor, increasing signal 21-fold, showing real-world potential