AI Models Show Promise for Personalized Schizophrenia Treatment But Face Generalization Hurdles
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Scientists showed AI models predict medication response for schizophrenia very accurately within the trial they were developed.
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However, models did not perform better than random predictions when used outside original trial.
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Models were highly context-dependent and could not be generalized across different studies/centers.
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Researchers are working to improve models by examining larger patient groups and datasets.
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Goal is to use AI models to enable more targeted treatment for mental health problems.