Posted 3/4/2024, 1:44:30 PM
AI Model Predicts Drug Interactions Early to Improve Safety
- AI machine learning model can predict which drugs may interfere with one another based on shared drug transporters
- Researchers trained model on data about 20+ medications and drug transporters in intestinal tissue models
- Model predicted 58 previously unknown drug-transporter interactions, 7 of which were validated in mouse studies
- Model's predictions for interactions between common medications like digoxin and doxycycline were confirmed in hospital patient data
- AI method could improve drug safety by identifying harmful interactions earlier in development process