New AI Model BigRNA Predicts Gene Regulation, Identifies Disease Variants, and Designs RNA Therapeutics

Deep Genomics introduces BigRNA, an AI foundation model that predicts tissue-specific gene regulation and designs RNA therapeutics.
BigRNA outperforms current deep learning models at predicting regulatory protein and miRNA binding sites.
BigRNA accurately identifies disease variants and mechanisms, like polyadenylation site changes in syndromic X-linked microphthalmia.
Without additional training, BigRNA designs effective steric blocking oligos, including for Wilson disease and SMA genes.
BigRNA is the first model capable of discovering new RNA biology and designing tailored RNA therapeutics.

businesswire.com

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