Mapping Over 1 Million Brain Cells Reveals Links Between Cell Types and Neuropsychiatric Disorders

Researchers mapped over 1 million human brain cells to reveal links between specific cell types and neuropsychiatric disorders like schizophrenia and Alzheimer's.

The maps detail differences in gene activity across 107 distinct brain cell subtypes in 42 brain regions.

Researchers developed AI tools to predict how gene variants may contribute to psychiatric disease risk.

The project is part of the NIH BRAIN Initiative launched in 2014 to revolutionize understanding of the brain through new neurotechnologies.

Scaling up to more brains will bring scientists closer to understanding neuropsychiatric disorders and developing new therapies.